Anti-GluR2 Monoclonal Antibody

Product Name

Anti-GluR2 Monoclonal Antibody

View all GRIA2 Antibodies

SKU/Catalog Number

M02905

Size

100 μl

Form

Liquid

Description

Boster Bio Anti-GluR2 Monoclonal Antibody catalog # M02905. Tested in WB, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-GluR2 Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M02905)

Host

Rabbit

Contents

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.

Clonality

Monoclonal

Clone Number

ACIB-7

Isotype

Rabbit IgG

Immunogen

A synthesized peptide derived from human GluR2 Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M02905 is reactive to GRIA2 in Human, Mouse, Rat

Applications

M02905 is guaranteed for IP, IF, ICC, WB Boster Guarantee

Observed Molecular Weight

136 kDa

Calculated molecular weight

98.821kDa

Background of GRIA2

F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Reconsitution

Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB 1:500-1:2000
ICC/IF 1:50-1:200
IP 1:50

Validation Images & Assay Conditions

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All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.

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All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.

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All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.

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Western blot analysis of GluR2 expression in (1) Human fetal brain lysate; (2) Mouse brain lysate.

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All lanes use the Antibody at 1:5K dilution for 1 hour at room temperature.

Gene/Protein Information For GRIA2 (Source: Uniprot.org, NCBI)

Alternative Names

AMPA 2; AMPA2; GluA2; GluR2; GLURB; GluR-K2; glutamate receptor, ionotropic, AMPA 2; GRIA2; HBGR2 GRIA2 GLUR2, GLURB, GluA2, GluR-K2, HBGR2, NEDLIB, gluR-2, gluR-B glutamate ionotropic receptor AMPA type subunit 2 glutamate receptor 2|AMPA-selective glutamate receptor 2|glutamate receptor, ionotropic, AMPA 2

For more info on GRIA2, check out the GRIA2 Infographic

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In this infographic, you will see the following information for GRIA2: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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